Contribution of CDP/Cux, a Transcription Factor, to Cell Cycle Progression
نویسندگان
چکیده
منابع مشابه
Contribution of CDP/Cux, a transcription factor, to cell cycle progression.
CCAAT-displacement protein/Cut homeobox (CDP/Cux) was initially identified as a transcriptional repressor. However, a number of studies have now suggested that CDP/Cux is a transcriptional activator as well. Stable DNA binding activity of CDP/Cux is up-regulated at the G(1)/S transition by two mechanisms, dephosphorylation by the Cdc25A phosphatase and proteolytic processing to generate a 110 k...
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Cell cycle transitions are often triggered by the proteolysis of key regulatory proteins. In Caulobacter crescentus, the G1-S transition involves the degradation of an essential DNA-binding response regulator, CtrA, by the ClpXP protease. Here, we show that another critical cell cycle regulator, SciP, is also degraded during the G1-S transition, but by the Lon protease. SciP is a small protein ...
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PURPOSE To test the hypothesis that overexpression of the transcription factor E2F2 promotes cell cycle progression in nonproliferating corneal endothelial cells. METHODS Ex vivo rabbit corneas were transfected with a lipid transfection reagent and either a control plasmid containing full-length cDNA for enhanced green fluorescent protein (pIRES2-EGFP) or a plasmid containing full-length cDNA...
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BLOCKINcycle. 23 24. CC-BY-NC-ND 4.0 International license peer-reviewed) is the author/funder. It is made available under a The copyright holder for this preprint (which was not .
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ژورنال
عنوان ژورنال: Acta Biochimica et Biophysica Sinica
سال: 2007
ISSN: 1672-9145,1745-7270
DOI: 10.1111/j.1745-7270.2007.00366.x